Current Type II Medication
Sulfonylureas
> Generic: Glipizide
> Mechanism of Action: Stimulate increased insulin production
~ Eventually the pancreas wears out
Biguanides
> Generic: Metformin
> Mechanism of Action: Decrease hepatic glucose production
> Doesn’t overwork pancreas
~ Helps body better use insulin that already exists
~ Decreases resistance to insulin
> Can produce bad stomach cramps
Thiozolidinediones
> Generic: Pioglitizone, Rosiglitizone
> Mechanism of Action: increase central and peripheral insulin sensitivity
Alpha Glucosidase Inhibitors
> Generic: Acarbose, Miglitol
> Mechanism of Action: Interferes with carbohydrate absorption in the gut
Meglitinides
> Generic: Replaglinide, nateglinide
> Mechanism of Action: Stimulate increased insulin production of short duration
Close Window